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GHDDI正在迅速成长!具备一定规模、拥有杰出药物研发能力的团队是中心发展的基石。我们寻求有突出能力的科学家及实验研究工作人员、有经验的管理团队以及专业运营团队加入我们! 中心为积极主动、有创造力和创业精神的员工提供多元化、充满活力的工作环境以及良好的发展机会。我们的员工认同GHDDI的使命,分享共同的愿景,携手致力科学和人类健康事业的发展。
研究助理(微生物学家),疾病生物学  

主要职责

  • 开展普通微生物培养、耐药性检测及其他药物高通量筛选相关的生物学实验。

  • 在P-2实验室环境下进行对人或动物病原菌,病原体的微生物实验。

  • 辅助完成微生物遗传操作和指导员交代的其他科研任务。


任职要求

  • 微生物学或分子生物学、生物化学等相关专业全日制硕士研究生毕业,或优秀微生物专业本科毕业生,具有扎实的专业基础知识。

  • 熟练掌握经典微生物学相关实验技术,例如微生物培养、分离鉴定,细菌染色、光学显微镜使用,微生物生长曲线绘制,系列稀释平板计数,药物MIC测定等,掌握分子克隆、DNA序列分析,蛋白表达纯化、Western blot等基本的分子生物学操作。

  • 具有广泛的病原菌培养经验、或药物高通量筛选等相关研究经验者优先。

  • 具有高度的自我激励及团队合作能力、创造性解决问题的能力,能保质保量完成科研任务,具有基本的英语口头和书面表达能力。

  • 具备严谨的科研素养,能对实验记录和电子文档进行归档整理。


工作地

北京


关于我们

全球健康药物研发中心(Global Health Drug Discovery Institute,简称“GHDDI”)是由清华大学和比尔及梅琳达·盖茨基金会发起,北京市科学技术委员会代表北京市人民政府联合出资支持下成立的一个独立运营、非营利性质的全球公共卫生与药物创新机构。中心关注全球健康问题,致力发展杰出的生物医药研究与开发能力,建设新药研发和转化的创新平台,为解决发展中国家面临的突出疾病挑战做出贡献。


联系我们

申请者请发送个人简历以及代表性论文清单至 career@ghddi.org

Scientist/ Investigator (Host Immune Defense), Disease Biology  

Key Responsibilities

  • Study the host response and mechanism of action to infection in various infectious diseases including TB, malaria, viral infection and other public health diseases.

  • Identify the interacting signaling pathways and the key proteins in host cells in responding to pathogens and other environmental challenges.

  • Isolate and establish primary immuno-cell culture based on the special properties of various types of immune cells.

  • In collaboration with assay development group to identify biochemical or cellular assays to screen for cmpds improving host immune system against challenges.

  • Develop additional assays for hit validation and triage.

  • Work closely with medichem group to examine in vitro efficacy of cmds as a guidance to SAR.

  • Responsibilities may vary depending on the training background and experience.


Minimum Requirements

  • PhD degree in immunology, cell biology, molecular biology or the related biological sciences with 0-6 year experience.

  • In depth understanding of and working experience with human innate and/or adaptive immune-regulation.

  • Familiar with immune cell types and their properties/markers and techniques in the field.

  • Good team player, excellent collaboration and communication skills.

  • Oral and written skill of English in scientific communication.

  • Scientific integrity is a must; candidate should be professional in maintaining lab notebooks and electronic files.


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world's most pressing disease challenges faced by many developing countries.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org

研究助理(寄生类),疾病生物学  

主要职责

  • 能够安全高效地操作寄生性疾病生物学实验。

  • 组织并管理实验室的日常工作。

  • 维护、培养多种细胞及细胞系库。

  • 协助其他科研人员完成实验。

  • 管理物资和实验室库存,保证所有仪器设施正确运行。


任职要求

  • 拥有在生物学或其它相关领域的本科或硕士, 0-5年研究经验。

  • 具有优秀的组织能力,能够与国际学术界和相关疾病专家有效交流。

  • 拥有基本体外细胞培养和分子生物学技能。

  • 能够严谨地维护实验记录和其它数据文件。

  • 具有基本英语沟通能力。


工作地

北京


关于我们

全球健康药物研发中心(Global Health Drug Discovery Institute,简称“GHDDI”)是由清华大学和比尔及梅琳达·盖茨基金会发起,北京市科学技术委员会代表北京市人民政府联合出资支持下成立的一个独立运营、非营利性质的全球公共卫生与药物创新机构。中心关注全球健康问题,致力发展杰出的生物医药研究与开发能力,建设新药研发和转化的创新平台,为解决发展中国家面临的突出疾病挑战做出贡献。


联系我们

申请者请发送个人简历以及代表性论文清单至 career@ghddi.org

Parasitologists & Microbiogist (various levels), Disease Biology  

Key Responsibilities

  • Design screening cascades and implement HTS, hit triage and interpret the results of DMPK and toxicological profiling.

  • Work closely with medicinal chemistry, structural biology and DMPK teams and help select and advance screening hits.

  • Explore molecular targets (mode of actions) of hit/lead/candidate compounds.

  • Initiate, facilitate and organize domestic and international collaborations with academic and industrial partners.

  • Take a leadership role for data analysis and nominate strategies.

  • Mentor team members and help them trouble shoot.

  • Develop written reports and oral presentations for monthly and quarterly meetings and annual reports.

  • Present findings at international meetings and publish to scientific journals.


Minimum Requirements

  • Have a Ph.D in parasitology, microbiology, vector biology, molecular biology, chemical biology or any related area with minimum of 0-2 years of post-graduate research experiences for the Institute Fellow position and 2 to 7 years experiences for the Scientist or Investigator position. MDs who are interested in tropical medicine/public health or DVMs who are interested in tropical zoonotic/livestock diseases or comparative medicine are also encouraged to apply.

  • Have broad understanding of cutting-edge technologies and challenges in anti-microbial drug discovery for neglected diseases.

  • Have basic knowledge of pre-clinical drug discovery efforts including in vitro/in vivo assay design, compound profiling/triaging, understanding of pharmacokinetics and pharmcodynamics, and medicinal chemistry.

  • Have excellent oral and written English communication skills.

  • Be capable of working in an interactive and multidisciplinary team environment while conducting self-directed research within broader goals set by the group.

  • Possess excellent organizational skills and the ability to interact effectively with an international network of laboratories and disease experts.

  • Be meticulous in maintaining lab notebooks and data files.

  • The applicants should demonstrate a proven track record of scientific achievements and creative problem-solving skills.

  • Those with in-depth knowledge in genome editing, chemical biology, systems biology, parasite genomics, biomarker discovery, host immunity, vector biology, or in vivo animal model studies will be preferred.

  • Hands-on experiences in in vitro cell culture, microscopy, flow cytometry and molecular biology are ideal, but not required.


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world's most pressing disease challenges faced by many developing countries.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org

兽医研究助理(比较医学),疾病生物学  

主要职责

  • 管理小型实验动物的日常活动。

  • 维护多种免疫活性及免疫缺陷老鼠。

  • 与其他科研人员一起,帮助进行体内药效研究(寄生接种,药物剂量,血液和组织抽样,体内呈像)。

  • 管理实验消耗品及动物房日常维护,并确保所有仪器/设备正确运行。


任职要求

  • 拥有在生物学、动物学或其它相关领域的本科或硕士学历,至少两年实验动物操作经验。

  • 具有基本小鼠大鼠实验相关技能,包括填喂法饲养,腹膜内和尾部注射。

  • 具有基本英语沟通能力。

  • 能够在跨学科环境下工作。

  • 具有优秀的组织能力,能够与国际学术界及疾病专家进行有效交流。

  • 能够严谨地记录及维护实验笔记和其它数据文件。


工作地

北京


关于我们

全球健康药物研发中心(Global Health Drug Discovery Institute,简称“GHDDI”)是由清华大学和比尔及梅琳达·盖茨基金会发起,北京市科学技术委员会代表北京市人民政府联合出资支持下成立的一个独立运营、非营利性质的全球公共卫生与药物创新机构。中心关注全球健康问题,致力发展杰出的生物医药研究与开发能力,建设新药研发和转化的创新平台,为解决发展中国家面临的突出疾病挑战做出贡献。


联系我们

申请者请发送个人简历以及代表性论文清单至 career@ghddi.org

Chief Scientific Officer  

About the Chief Scientific Officer

The Chief Scientific Officer (CSO) will be working with the Institute CEO and Board to develop and manage the Institute's scientific R&D. The CSO will be responsible for developing and managing a world class research team to deliver drug candidates for diseases disproportionately impacting the world's poorest populations. Moreover, the CSO will be responsible for establishing and maintaining scientific collaborations with leading organizations in drug discovery and global health product development. The CSO will play a key role in engaging with GHDDI's Scientific Advisory Committee.
We are looking for a candidate with solid and visionary leadership skills and scientific ability, who is enthusiastic about working in a fast paced, dynamic environment. Additionally, this person should be passionate about taking a key role in shaping the vision and direction of a groundbreaking drug discovery institute. The candidate will have a Ph.D. in a relevant scientific discipline. A demonstrated ability to take initiative and engage in innovative problem solving is critical. A successful candidate must have a track record of success in broad drug discovery research and development, supported by publications and external presentations. Candidates must possess strong written and oral communication skills and the ability to drive results.


Key Responsibilities

  • Oversee all drug discovery projects and scientific operations to ensure the organization meets its scientific objectives.

  • Lead and manage the development of annual scientific goals, including obtaining and acting upon inputs from the Board of Directors, the Scientific Advisory Committee and collaborators.

  • Work closely with the CEO and other executives to ensure that the Board of Directors are well informed. Specifically, responsible for reporting and obtaining feedback on scientific objectives to the Board of Directors.

  • Forge deep, lasting relationships with GHDDI collaborators, including Tsinghua University, Calibr, and product development partners, and funding partners including the Bill & Melinda Gates Foundation and the Beijing Science and Technology Innovation Group.

  • Work with the CEO and other executive officers to manage overall business objectives.

  • Set clear expectations, give appropriate autonomy, and guide team members; manage performance by providing feedback, guidance/teaching, and development opportunities.

  • Ensure up to date knowledge of developments in drug discovery research and practices, and timely dissemination of this knowledge.

  • Ensure that the integrity and profile of GHDDI within the scientific community are maintained at a high level, consistent with the requirements of the business.

  • Develop and ensure that systems, capabilities, and resources are in place to optimize productivity and probability of success of GHDDI scientific team.

  • Oversee the overall management of the laboratory team, such as by ensuring adherence to an agreed upon budget, building and developing a world class team, and identifying technology and other needs.

  • Represent GHDDI in the scientific community, including representing GHDDI at scientific conferences and communicating through scientific presentations and publications.

  • Ensure that GHDDI develops and adheres to policies on Health, Safety and Environment.


Qualifications Education

  • Ph.D. or equivalent in a relevant scientific discipline required.


Required Experience and Skills

  • At least 10 years of drug discovery or development experience in the biotechnology or pharmaceutical industry (or relevant/equivalent experiences in academia), with track record of success.

  • Innovative and strategic thinker.

  • Ability to travel domestically and internationally.

  • Demonstrable ability and enthusiasm for identifying, setting, and meeting critical deliverables.

  • Ability to build strong relationships with key stakeholders.

  • Dynamic self-starter with a drive for results and ability to motivate others to do their best.

  • Ability to cel